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CFDA 93.788: Opioid Affected Youth and Families Initiative

Targeted federal funding for community-level interventions in opioid-affected populations. Heavily competitive but high mission-fit for nonprofits already serving rural and underserved communities.

Typical award
$300,000 – $1,000,000 per year, typically over 3-4 years
Eligible applicants
  • 501(c)(3) nonprofits
  • Federally Qualified Health Centers (FQHCs) and look-alikes
  • Public and private IHEs (medical schools, schools of social work)
  • State, county, city, and tribal governments
  • Public and tribal-run health systems

What this CFDA funds

Multi-year cooperative agreements supporting OUD/SUD prevention, treatment access expansion, peer-recovery infrastructure, and workforce training in HRSA-designated rural and underserved areas. Many awards target the rural communities opioid response (RCORP) framework: Planning year, Implementation 3 years.

What winning applicants look like

FQHC consortia, regional behavioral-health collaboratives, and rural-health-network nonprofits with documented community-engagement processes. Past performance on similar HRSA awards (RCORP, BHWET) is a major scoring lift. State-level strategic alignment letters help significantly.

Common pitfalls + things to know

HRSA NOFOs require a logic model with specified evaluation metrics — generic logic models are rejected. Population definitions must match HRSA's underserved-community designation (the HPSA or MUA shapefiles). Indirect-rate caps in the NOFO are common (often 10% MTDC). Cost-sharing is sometimes required.

Related CFDAs to also explore

Audiences who use this CFDA

If you fall into one of these audience groups, the audience guide gives you the broader picture of all federal funding streams you qualify for — not just CFDA 93.788.

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Always verify in the official source. CFDA program details, eligibility, and award ranges change with each annual NOFO cycle. Confirm at sam.gov/content/assistance-listings or the agency's program office before you build an application strategy. This page is editorial reference, not an official agency notice.