Burns Media Intelligence for Professionals
← All CFDA guides
CFDA / Assistance Listing · Reference

CFDA 81.049: Office of Science Financial Assistance Program

SC is the Nation’s largest Federal sponsor of basic research in the physical sciences and the lead Federal agency supporting fundamental scientific research for our Nation’s energy future.

Also known as
(Advanced Scientific Computing Research (ASCR), Basic Energy Sciences (BES), Biological and Environmental Research (BER), Fusion Energy Sciences (FES), High Energy Physics (HEP), Nuclear Physics (NP), Workforce Development for Teachers and Scientists (WDTS), Small Business Innovation Research (SBIR) Program and Small Business Technology Transfer (STTR) Program), Isotope R&D and Production (DOE IP), Accelerator R&D and Production (ARDAP))
Assistance types
PROJECT GRANTS (COOPERATIVE AGREEMENTS)
Official listing
View on SAM.gov →

Objectives

SC is the Nation’s largest Federal sponsor of basic research in the physical sciences and the lead Federal agency supporting fundamental scientific research for our Nation’s energy future. SC is an established leader of the U.S. scientific discovery and innovation enterprise. Over the decades, SC investments and accomplishments in basic research and enabling research capabilities have provided the foundations for new technologies, businesses, and industries, making significant contributions to our nation’s economy, national security, and quality of life. Additional descriptions of recent science discoveries can be found at https://science.osti.gov/Science-Features/Science-Highlights. SC accomplishes its mission and advances national goals by supporting: - Science for energy, economic and national security?building a foundation of scientific and technical knowledge to spur discoveries and innovations for advancing the Department’s mission. SC supports a wide range of funding modalities from single principal investigators to large team-based activities to engage in fundamental research on energy production, conversion, storage, transmission, and use, and on our understanding of the earth systems. - The frontiers of science—exploring nature’s mysteries from the study of fundamental subatomic particles, atoms, and molecules that are the building blocks of the materials of our universe and everything in it to the DNA, proteins, and cells that are the building blocks of life. Each of the programs in SC supports research probing the most fundamental disciplinary questions. - The 21st Century tools of science—providing the nation’s researchers with 28 state-of-the-art national scientific user facilities, the most advanced tools of modern science, propelling the U.S. to the forefront of science, technology development, and deployment through innovation.

Eligible applicants

Except where a program solicitation establishes more restrictive eligibility criteria, individuals and organizations in the following categories may submit proposals: Institutions of higher education; National Laboratories; Nonprofit and for-profit private entities; State and local governments; and consortia of entities described above.

Financial assistance range

$10,000 to $2,500,000; $250,000.

Get matched on every CFDA 81.049 NOFO automatically

Grant Wire Pro emails you a daily digest of every Grants.gov / SBIR / NSF / NIH NOFO matching your org type, applicant eligibility, CFDAs (including 81.049), and keywords — with AI fit scoring and applicant-eligibility analysis. 7-day free trial, $20/mo after.

Start 7-day free trial →

Reference data sourced from SAM.gov Assistance Listings. The authoritative source for application requirements, deadlines, and award amounts is the official SAM.gov listing linked above. This page is editorial reference, not an official notice.